Slam Bio is a biotech company developing a platform of very promising first-in-class human bispecific monoclonal antibody and antibody-drug conjugates (ADCs) targeting the most challenging blood cancers. SLAM Bio’s lead assets demonstrate a profound activity against these cancers in preclinical models.
Our mission is to pioneer paradigm-changing therapies that offer a beacon of hope to patients, ushering in a new era of breakthroughs in the fight against cancer.
Our seasoned and proven leadership team—led by CEO Steve Potts; Chairman and Co-Founder, Rick Heinick; SAB Chair and Co-Founder, Dr. Steven Rosen; along with an experienced oncology team—has been involved in multiple successful drug development programs and exits. The team includes scientists, clinicians and business professionals, all who bring unique skills and perspectives.
Innovation is at the heart of what we do at SLAM Bio.
Our primary indication is acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Our secondary indications are a broad spectrum of both T and B cell Non-Hodgkin lymphomas including cutaneous and peripheral T-cell lymphomas and both diffuse large B-cell and follicular lymphomas .
Our novel humanized monoclonal antibodies target SLAM F5 (CD84) a cell surface adhesion molecule which is part of the signaling lymphocytic activation molecule (SLAM) family of receptors. The lead antibodies target SLAMF5 (CD84) with high affinity, compelling efficacy, and restricted normal tissue expression.
We have a broad and fresh IP portfolio of more than 17 antibodies. Our Phase I clinical trials will be initiated in the first half of 2026 for hematologic cancers.
We have partnered with two leading cancer research institutions, City of Hope and the Weizmann Institute, to develop innovative solutions with the potential to extend and enhance the lives of people with cancer.
IFLI’s investment to accelerate development of groundbreaking therapies and novel targets for blood cancers, including follicular lymphoma
Diamond Bar, CA – March 4, 2025 – SLAM BIO, a company focused on developing first-in-class bispecific human monoclonal antibody T cell engagers and antibody-drug conjugate (ADC) therapies for the most challenging blood cancers, today announced a strategic investment from The Institute for Follicular Lymphoma Innovation (IFLI). This collaboration will accelerate the development of novel treatments for a range of blood cancers, including follicular lymphoma, and pave the way for better outcomes for patients battling life-threatening diseases.
SLAM BIO is advancing a groundbreaking platform targeting a unique family of proteins, with therapies designed to both directly kill cancer cells while activating the immune system against the malignancy. Backed by a recent $10 million funding round, the company is accelerating its pipeline to bring novel treatments to the clinic for hematologic cancers, including follicular lymphoma (FL), acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and cutaneous T-cell lymphoma (CTCL).
IFLI’s support demonstrates its dedication to advancing innovative research and clinical trials focused on follicular lymphoma, while also helping to advance SLAM BIO’s novel platform to conquer other life-threatening blood cancers.
“We’re excited to partner with SLAM BIO in their mission to improve outcomes for patients with follicular lymphoma and other blood cancers,” said Dave McCullagh, Managing Director of IFLI. “Their innovative approach aligns with our goals, and we look forward to accelerating these therapies for those in need.”
“IFLI is thrilled to collaborate with SLAM BIO to catalyze the development of a promising new target with high potential for treating specific B-cell malignancies,” said Michel Azoulay, MD, Chief Medical Officer of IFLI.
“This investment from IFLI is a strong endorsement of SLAM BIO’s work,” said Rick Heinick, Founder and Chairman of SLAM BIO. “With this partnership, we’re in a stronger position to accelerate life-saving treatments for patients battling blood cancers with limited options.”
Dr. Steven Rosen, Executive Vice President of City of Hope, emphasized, “With IFLI’s support, SLAM BIO’s transformative therapies have the potential to change the way we treat follicular lymphoma and other blood cancers, offering new hope to patients in need.”
About SLAM BIO:
SLAM Bio is pioneering innovative cancer therapies, developing first-in-class human monoclonal antibodies, bispecifics and ADCs designed to target a family of proteins with high expression in a broad spectrum of blood cancers. The company's therapeutic platform has the potential to transform cancer treatment and significantly improve the lives of patients with life-threatening conditions like AML, MDS, CTCL and FL. Learn more at www.slambio.com.
About IFLI:
The Institute for Follicular Lymphoma Innovation (IFLI) is a global, non-profit, private foundation dedicated to accelerating the development of innovative treatment options for patients with follicular lymphoma (FL). IFLI supports cutting-edge research and technology to lead to the development and commercialization of novel therapeutics and/or biomarkers for the treatment of FL, and to understand the biology of FL. The foundation deploys its budget across grants, project-based partnerships, and venture philanthropic investments to achieve its innovation goals. IFLI promotes collaboration and works to enable data sharing and the exchange of knowledge and expertise among researchers and institutions advancing FL research. Learn more at www.i-fli.org.
Media Contact, SLAM BIO, Inc.
Madelyn De Los Santos,
Director of Communications
THOUSAND OAKS, CA – January 3, 2024. SLAM BioTherapeutics, Inc., a promising biotechnology company, dedicated to novel oncology and autoimmune therapies, announces a seed round of over $8 Million to advance its portfolio of antibodies. The company’s suite of antibodies targets a novel cell surface receptor expressed in the tumor microenvironment.
Leading the investment was Schwartz Capital Group. The funds raised will support SLAM Bio’s pre-clinical development efforts and facilitate Investigational New Drug (IND) enabling studies for its lead asset.
SLAM Bio was co-founded by distinguished cancer researcher Dr. Steven Rosen, Emeritus Director of Beckman Research Institute of City of Hope, veteran biotech executive Rick Heinick and Prof. Idit Shachar from the Weizmann Institute. The company is targeting the signaling lymphocytic activation molecule (SLAM) family of receptors, which modulate myeloid-derived suppressor cells (MDSCs), B regulatory and T regulatory cells and associated activation of cytotoxic T and Natural Killer cells.
Rick Heinick, Chairman of SLAM Bio, commented, “These advances are a textbook case of how new discoveries from a seemingly well- explored area of bioscience can lead to breakthrough therapies for patients with hematologic and solid tumor cancers. This team has demonstrated remarkable capability to execute, and we are excited about the future here.”
“SLAM Bio’s portfolio of novel antibodies has demonstrated promising preclinical results with the potential to curb the growth and spread of a broad spectrum of cancers. We are excited to be a part of this important mission,” remarked Ted Schwartz, founder of Schwartz Capital Group and a lymphoma survivor.
About SLAM BioTherapeutics
Slam Bio is a preclinical stage biotech company developing antibody therapies for cancer and autoimmune diseases. SLAM Bio’s lead assets have first-in-class potential and have demonstrated a profound effect on the tumor micro-environment in preclinical models.
More information available at www.slambio.com.
Visit us on social media:
LinkedIn
Please send us a message for more information.
3148 Versaille Court, Thousand Oaks, California 91362, United States